Transition metals activate TFEB in overexpressing cells
نویسندگان
چکیده
منابع مشابه
Transition metals activate TFEB in overexpressing cells
Transition metal toxicity is an important factor in the pathogenesis of numerous human disorders, including neurodegenerative diseases. Lysosomes have emerged as important factors in transition metal toxicity because they handle transition metals via endocytosis, autophagy, absorption from the cytoplasm and exocytosis. Transcription factor EB (TFEB) regulates lysosomal biogenesis and the expres...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2015
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20140645